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Michael Thompson

Mike Thompson
Unit: 
Chemistry and Chemical Biology
Bio: 
The Thompson Lab creates new experimental methods that combine temperature perturbations with X-ray crystallography, allowing them to explore the conformational landscapes of protein molecules and identify the structural states that define their biological activities.
Research Program: 
Molecular motion is critical for protein function, but it remains challenging to study the structural dynamics of complex molecules in atomic detail. My goal is to develop new types of structural and biophysical experiments that transcend the limitations of traditional techniques, allowing us to map structural interconversions at high spatial and temporal resolution.