Research in my lab addresses both clinical and basic science questions regarding electrolyte and water regulation in a variety of animal models including seals and dolphins. Clinically, I am continuing investigating the role aldosterone plays in exacerbating high blood pressure and the effects of aldosterone antagonism on renal sodium and potassium regulation. I also pursue studies that address the link between diabetes and obesity with hypertension. From the perspective of basic science I am interested in the physiological mechanisms marine adapted vertebrates use to regulate water and electrolytes during a variety of altered environmental conditions such as prolonged food deprivation or extended fresh water exposure. Comparative species are viable models to address several of my clinical questions.